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簡(jiǎn)要描述：Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in prese
產(chǎn)品型號(hào)：bsm-54298R廠(chǎng)商性質(zhì)：生產(chǎn)廠(chǎng)家更新時(shí)間：2025-03-02訪(fǎng) 問(wèn) 量： 131產(chǎn)品分類(lèi)
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